If you watch one piece of media this year, please make it this one.  It is about 90 minutes in length and is absolutely riveting.  I'm actually listening to it again this morning as I work through email.

Carnegie Mellon Professor Randy Pausch, who is dying from pancreatic cancer, gave his last lecture at the university Sept. 18, 2007, before ... all » a packed McConomy Auditorium. In his moving talk, "Really Achieving Your Childhood Dreams," Pausch talked about his lessons learned and gave advice to students on how to achieve their own career and personal goals.

I'm a little late to posting this one, but absolutely had to share. 

Some additional coverage on the Wall Street Journal Online (A Beloved Professor Delivers The Lecture of a Lifetime) and Robert Scoble's Inspiration post.

Scoble, you lucky bugger. :-)   I remember you telling me about Randy after your trip to Carnegie Mellon.   Man, that was inspiring.  Thank you Randy Pausch, I needed this kick in the pants today.